Invité Mar 19 Juil 2011 - 21:37De CCSVI-Alliance :
18/06/2011
Rapport du Dr Mehta, étude à Albany, 125 malades SEP tq définis par neuros, 54% relapse remitting; 34% secondary progressive; and 12% primary progressive. All patients underwent evaluation via selective venography of their bilateral internal jugular veins (IJV), as well as the azygous veins (AZ). Only those with evidence of greater than 50% stenosis underwent percutaneous angioplasty. The total number of lesions (places where there is a stenosis or restriction in a vein) was 230 in the 125 study patients.
Following angioplasty, patients were seen at 3 months and 6 months, and underwent objective evaluations via duplex ultrasound, EDSS, and timed 25-foot walk, as well as subjective evaluations by MS quality of life-54 (MSQOL), and modified fatigue impact score (MFIS).
The EDSS evaluation revealed “statistically significant improvement” in relapsing remitting MS patients and “a trend towards improvement” in those with secondary progressive MS. There was no difference noted in the EDSS scores of primary progressive MS patients partly due to the inability of those patients to ambulate both before and after the procedure.
Based on the Liberation study results to date, Dr Mehta concluded that for MS patients with CCSVI, angioplasty of the internal jugular veins and azygous veins appears to be safe, and associated with MS patients experiencing “significant clinical, as well as quality of life improvements”.
Un peu la flemme de traduire, text très long. J'ai mis le principal (en anglais, sorry).
Globalement : bcp de blocages veineux chez patients SEP (il ne parle pas de contrôles sains, grave erreur), amélioration ap angioplastie surtout pour les SEP rémittentes, un peu pr les 2aires, presque pas pr les 1aires. MAIS mesure EDSS => patients peuvent marcher, ce qui n'était pas tjs le cas, donc efficacité limitée de la mesure EDSS. Qualité de vie ???
https://www.facebook.com/notes/ccsvi-alliance/exclusive-ccsvi-alliance-at-s, moy d'âge 47 ans,ociety-of-vascular-surgeons-meeting-in-chicago-comp/242891665736202
